Draper invested in and contributed to the development of Skype (acquired by eBay, now sold to Microsoft), Baidu, Overture (acquired by Yahoo!), Parametric Technology, Hotmail (acquired by Microsoft), Tumbleweed Communications, PLX Technologies, Digidesign (acquired by Avid), Preview Travel (acquired by Travelocity), Four11 (acquired by Yahoo!), Combinet (acquired by Cisco), and Redgate (acquired by AOL), among others.
Draper launched the DFJ Global Network, an international network of venture capital funds with offices in more than thirty cities around the globe. He founded or co-founded Wasatch Ventures (Salt Lake City), Zone Ventures (LA), Draper Atlantic (Reston), Draper Triangle (Pittsburgh), Timberline Ventures (Woodland, WA), DFJ EPlanet (global), Polaris Fund (Anchorage), Draper Fisher Jurvetson Gotham (NYC), DFJ Frontier (Sacramento and Santa Barbara), and DFJ Dragon (Shanghai). Draper is featured as a keynote speaker in entrepreneurial conferences worldwide.
Draper is Founder and Chair Emeritus for The BizWorld Foundation that develops programs that teach children about business, entrepreneurship and finance in the US and around the world.
He served on the California State Board of Education in 1998–99. He launched a statewide cyber-initiative on school choice for the November 2000 California General Election.
Draper has a BS in Electrical Engineering from Stanford University, and an MBA from Harvard Business School.
Draper is a recurring star in The Naked Brothers Band TV series on Nickelodeon as Principal Schmoke. Draper is the uncle to the show’s stars, Nat and Alex Wolff. Moreover, his sister actress/writer Polly Draper created and produced the show. His children—actress Jesse Draper, Adam Draper, Billy Draper, and Eleanor Draper—also have starring roles in the project.
Draper is also a global board member of Endeavor and a member of the board of directors of Wigix, Inc.
Draper was named an Honorary Patron of the University Philosophical Society, Trinity College, Dublin.